Implantation of platelet-rich fibrin and cartilage granules facilitates cartilage repair in the injured rabbit knee: preliminary report

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Implantation of platelet-rich fibrin and cartilage granules facilitates cartilage repair in the injured rabbit knee: preliminary report

Tzong-Fu Kuo, Ming-Fang Lin, Yun-Ho Lin, Ying-Chun Lin, Rou-Jen Su, Hui-Wen Lin, Wing P. Chan I Graduate Institute of Veterinary Medicine, National Taiwan University, Taiwan, Republic of China. II Department of Radiology, Wan Fang Hospital, Taipei Medical University, Taiwan, Republic of China. III Department of Pathology, School of Medicine, Taipei Medical University, Taiwan, Republic of China....

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Effects of Platelet-Rich Plasma & Platelet-Rich Fibrin with and without Stromal Cell-Derived Factor-1 on Repairing Full-Thickness Cartilage Defects in Knees of Rabbits

Background: The purpose of this study was to create biomaterial scaffolds like platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) containing stromal cell-derived factor-1 (SDF1) as a chemokine to induce hyaline cartilage regeneration of rabbit knee in a full thickness defect.Methods: We created a full thickness defect in the trochlear groove of thirty-six bilateral knees of eighteen matu...

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Platelet-rich plasma for articular cartilage repair.

Platelet concentrates have been gaining popularity for a number of applications in orthopedic surgery as a way to enhance both healing of various tissues and reduce pain. One major area of focus has been the effect of platelet-rich plasma (PRP) on stem cells and chondrocytes and the potential for PRP to enhance cartilage regeneration as well as reduce catabolic factors that lead to cartilage de...

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Efficacy of platelet-rich fibrin matrix on viability of diced cartilage grafts in a rabbit model.

OBJECTIVES/HYPOTHESIS The objective of this study was to compare the viability of cartilage grafts embedded in platelet-rich fibrin matrix (PRFM) wrapped with no material (bare diced cartilage grafts), oxidized methylcellulose (Surgicel), or acellular dermal tissue (AlloDerm). STUDY DESIGN Experimental study. METHODS In this study, six New Zealand rabbits were used. Cartilage grafts includi...

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Platelet-Rich Fibrin Facilitates Rabbit Meniscal Repair by Promoting Meniscocytes Proliferation, Migration, and Extracellular Matrix Synthesis

Although platelet-rich fibrin (PRF) has been used in clinical practice for some time, to date, few studies reveal its role as a bioactive scaffold in facilitating meniscal repair. Here, the positive anabolic effects of PRF on meniscocytes harvested from the primary culture of a rabbit meniscus were revealed. The rabbit meniscocytes were cultured with different concentrations of PRF-conditioned ...

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ژورنال

عنوان ژورنال: Clinics

سال: 2011

ISSN: 1807-5932

DOI: 10.1590/s1807-59322011001000026